复方夏天无片治疗轻度癌痛的临床观察

Clinical Observation on Treatment of Mild Cancer Pain with Compound Rhizoma Corydalis Decumbentis

关键词:  轻度癌痛  复方夏天无片  镇痛效果  不良反应

Key words:  mild cancer pain  compound Rhizoma Corydalis Decumbentis tablet  analgesic effect  side effect

摘要:

目的 观察复方夏天无片治疗轻度癌痛的疗效。方法 将76例符合入组标准的轻度癌痛病患者随机分成两组各38例。治疗组用复方夏天无片口服，每日3次，每次2片，连续使用2周。对照组用非甾体抗炎药双氯酚酸钠肠溶片，每日3次，每次50 mg，方法及疗程均与治疗组相同。结果 治疗组总有效率89.5%，对照组的总有效率88.2%，两组比较无显著性差异(P＞0.05)；治疗组不良反应发生率仅为7.89%，且症状比较轻微；而对照组双氯酚酸钠不良反应发生率为23.68%，尤其是胃肠反应及肝、肾功能损害比较突出，症状也比较明显，患者耐受性较差，经统计分析有极显著差异(P＜0.01)。结论 复方夏天无片治疗轻度癌痛与双氯酚酸钠肠溶片效果相似，但不良反应发生率少。

Abstract:

OBJECTIVE To observe the effect of compound Rhizoma Corydalis Decumbentis treating mild cancer pain. METHODS Seventy-six patients with the standard of mild pain were divided into two groups randomly. Thirty-eight cases in treatment group were given 2 tablets compound Rhizoma Corydalis Decumbentis each time, three times a day, lasting 2 weeks. Control group was given diclofenac sodium, 50 mg each time, three times a day. The methods and treating periods of treatment group and control group were same. RESULTS The total effective rate in treatment group was 89.5%, and control group was 88.2%, two groups have no significant difference (P>0.05). The side effect of treatment group was only 7.89%, and with minor symptoms, the control group was 23.68%, especially the gastrointestinal reaction and liver damage and kidney damage were very prominent, the symptoms were obvious, and patient tolerance was poor. By statistical analysis, there was significant difference(P<0.01). CONCLUSION The effect of treating mild cancer pain with compound Rhizoma Corydalis Decumbentis is the same with diclofenac sodium, while the side effect is less than the latter.