| 引用本文: | 陈立江,段洪云,张胜,刘玉峰,李丽,刘洋.大孔树脂对赤芍总苷吸附的初步研究[J].中国现代应用药学,2011,28(5):458-462. |
| CHEN Lijiang,DUAN Hongyun,ZHANG Sheng,LIU Yufeng,LI Li,LIU Yang.Research on Adsorption of Total Paeony Glycoside with Macroporous Resins[J].Chin J Mod Appl Pharm(中国现代应用药学),2011,28(5):458-462. |
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| 摘要: |
| 目的 研究D101、X-5、HPD-722、HP-20、AB-8、DM-130、HPD-600、NKA-9大孔树脂对赤芍总苷的吸附性能。方法 以芍药苷和芍药内酯苷为考察指标，通过静态吸附及解析实验，动态吸附和解析实验，对大孔树脂纯化赤芍总苷的工艺进行筛选。结果 AB-8大孔树脂对芍药苷和芍药内酯苷的比吸附量分别为42.23，53.70 mg·mL-1，比解析量分别为32.19，33.75 mg·mL-1。结论 AB-8大孔树脂的对赤芍总苷的分离纯化效果较好，具有良好的应用前景。 |
| 关键词: 大孔树脂 芍药苷 芍药内酯苷 吸附 解吸 |
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| 基金项目:辽宁省自然科学基金(20092015)；沈阳市科学技术计划项目(F10-205-1-28)；辽宁大学“211工程”三期建设项目-天然产物化学制药项目的资助 |
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| Research on Adsorption of Total Paeony Glycoside with Macroporous Resins |
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CHEN Lijiang,DUAN Hongyun,ZHANG Sheng,LIU Yufeng,LI Li,LIU Yang
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| Abstract: |
| OBJECTIVE To investigate the adsorption of total paeony glycoside by D101, X-5, HPD-722, HP-20, AB-8, DM-130, HPD-600, NKA-9. METHODS Through static adsorption and desorption as well as dynamic adsorption and desorption, the purification of total paeony glycoside by AB-8 macroporous resin was selected with paeoniflorin and albiflorin as investigation targets. RESULTS The adsorption quantity of AB-8 resin for paeoniflorin and albiflorin was 42.23, 53.70 mg·mL-1, and desorption quantity was 32.19, 33.75 mg·mL-1. CONCLUSION The isolation and purification capability of AB-8 macroporous resin is the best in the eight kinds of macroporous resins and have a favourable application perspective. |
| Key words: macroporous resin paeoniflorin albiflorin adsorption desorption |
