350例妇产科住院患者围手术期抗菌药物合理应用调查分析

Investigation on Reationality of Antibiotic Use in 350 Gynecologic and Obstetric Inpatients

关键词:  围手术期  抗菌药物  妇产科  合理性

Key words:  preoperative period  antibiotics  department of obstetrics and gynecology  rationality

摘要:

目的 分析我院妇产科住院患者围手术期抗菌药物使用情况，评价用药合理性。方法 随机抽取2009年5月1日—2010年4月30日在我院妇产科住院手术病例350例，对围手术期抗菌药物的合理性进行分析评价。结果 ①围手术期预防性抗菌药物使用率为100%；②用药种类：包括头孢菌素类、硝基咪唑类、磷霉素类、喹诺酮类；头孢菌素类占用药者的70.22%，硝基咪唑类、磷霉素类、喹诺酮类分别为18.16%，7.26%，2.42%；③平均每例用药天数：(3.05±2.02)d，占住院时间的45.23%；④给药时间：手术开始前2 h内用药者占100%，手术结束后用药的占0%。结论 我院给药时间、用药种类方面基本合理。预防性抗生素使用率过高，尤其I类切口预防使用抗菌药物及疗程不合理，需要进一步规范。

Abstract:

OBJECTIVE To investigate the prophylactic of antibiotics in preoperative period in our hospital and evaluate the reasonability of antibiotics usage. METHODS A total of 350 inpatients undergoing gynecologic and obstetric operation were randomly selected from May 1, 2009 to April 30, 2010. The preoperative prophylactic use of antimicrobial agents was investigated and analyzed. RESULTS ①Prophylactic antimicrobial agents were used in 350 cases(100%). ②The antimicrobial drugs included cephalosporin(70.22%), nitroimidazole(18.16%), fosfomycin (7.26%) and quinolones (2.42%). ③The average durations of antibiotic use were (3.05±2.02) d. ④100% of the patients received antibiotics within 2 h before operation. CONCLUSION Either the dosage or selection of antibiotic on the whole is reasonable in our hospital. Unreasonable use of preoperative prophylactic antimicrobial agents is common, especially for type I incision, and must be made further standardization.