|
摘要: |
3—[4—2(羟基乙基)哌嗪基]甲基—联苯对二酚(N22)为苯酚的衍生物,属非甾体类抗炎药。本文研究了N22对体外培养心肌细胞的作用,结果表明N22对大鼠体外培养心肌细胞搏动有明显的负性频率作用,并伴有搏动强度减弱作用;对自发性或由乌豆碱诱发的速发型心律失常有明显的对抗作用。 |
关键词: 3—[4—2(羟基乙基)哌嗪基]甲基—联苯对二酚 培养心肌细胞 负性频率 心律失常 |
DOI: |
分类号: |
基金项目: |
|
Effects of 3-[4-2(hydroxyethyl) piperazinyl] methyl-P-dihydoxydiphenyl on Cultured Heart Cells in vitro |
Zang Yuying et al.
|
Abstract: |
3-[4-2(hydroxyethyl) piperazinyl] methyi-P-dlhydoxydiphenyl derived from phenol was a nonsteroidal antimflammatory drug possessing antimflammatory and antipyretic-analgesic activities. Effect of 3-[4-2(hydroxyethyl)piperazingl] methyl-P-dihydoxydiphenyl o |
Key words: 3-[4-2(hydroxyethyl) piperazingl] methyl-P-dihydoxydiphenyl cultured myoca-rdial cells negative chronotropic action tachyarrhythmia |