5-Fu/PLGA 微球的制备

沈正荣;朱家蕙;张伟军;马臻

引用本文:	沈正荣;朱家蕙;张伟军;马臻.5-Fu/PLGA 微球的制备[J].中国现代应用药学,1993,(3):14-16.
	Shen Zhengrong Zhu Jiahuei Zhang Weijun Ma Zheng.Preparation of Poly(DL-lactide-co-glycolide)Microspheres Containing 5-Fluorouracile[J].Chin J Mod Appl Pharm(中国现代应用药学),1993,(3):14-16.

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5-Fu/PLGA 微球的制备
沈正荣;朱家蕙;张伟军;马臻

作者	单位
沈正荣;朱家蕙;张伟军;马臻

摘要:

以可生物降解高分子材料乳酸—羟乙酸共聚物(PLGA)为载体,以5—氟脲嘧啶(5-Fu)为活性药物,用相分离—凝聚法制备了可供肿瘤动脉栓塞化疗用微球,并进行了初步的微球体外药物释放试验。

关键词: 乳酸—羟乙酸共聚物 5—氟脲嘧啶相分离(?)凝聚法动脉栓塞

DOI：

分类号:

基金项目:

Preparation of Poly(DL-lactide-co-glycolide)Microspheres Containing 5-Fluorouracile

Shen Zhengrong Zhu Jiahuei Zhang Weijun Ma Zheng

Abstract:

An attempt is being made to develop poly(DL-lactide-co-glycolide)(PLGA)microspheres containing 5-fluorouracile(5-Fu)as a new anticancer preparation for tumourarterial chemoembolization therapy.Thus,PLGA was synthesized by ring-opening polymerization of DL

Key words: Poly(DL-lactide-co-glycolide) 5-Fluorouracile Microspheres