| 引用本文: | 魏尔清,王瑶尘,辛小华,卞如濂.白三烯拮抗剂ONO-1078对抗原诱导的豚鼠皮肤微血管渗漏的抑制作用[J].中国现代应用药学,1994,(6):6-8. |
| Wei Erqin, Wang Yaochen, Xin Xiaohua, Bian Rulian.nhibition of Antigen-induced Skin Microvascular Leakage in GuincaPigs by ONO-1078, a Leukotriene Antagonist[J].Chin J Mod Appl Pharm(中国现代应用药学),1994,(6):6-8. |
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| 摘要: |
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| 关键词: 4-氧-8-[对-(4-苯丁氧基)苯甲酰氢基]-2-(5-四唑基)-4H-1-苯并吡喃半水合物 微血 |
| DOI： |
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| 基金项目:浙江省自然科学基金 |
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| nhibition of Antigen-induced Skin Microvascular Leakage in GuincaPigs by ONO-1078, a Leukotriene Antagonist |
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Wei Erqin, Wang Yaochen, Xin Xiaohua, Bian Rulian
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| Abstract: |
| ONO-1078, a leukotriene antagonist,could significantly inhibited antigen-inducedextravasation of Evans blue in auricle skin in chlorpheniramine-pretreated actively. sensitizedguinea pigs, with ID50 values of 0.035 ma/kg for intravenous administration and |
| Key words: ONO-1078 { 4-oxo- 8 -[p-(phenylbutyloxy)benzoylamino 2 -(5-tetrazol)-4H-1 |
