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摘要: |
运用反相HPLC法测定人体血浆中的胺碘酮浓度。用己腈直接沉淀血浆蛋白在HPLC上直接进样,具有操作步骤简便的优点。0.5~10.0ug/ml范围内,日内变异系数4.5~6.1%;日间变异系数5.3~9.6%,最低检测限0.03ug,胺碘酮保留时间6.08min。 |
关键词: 高效液相色谱法 胺碘酮 人体血浆 浓度 |
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HPLC Assay for Amiodarone in Human Plasma |
Zhou Ying ; Ruan Zourong; Mao Hanwen
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Abstract: |
A reversed-phase high performance liquid chromatographic assay is described forthe determination of amiodarone in human plasma. The advantage of the method is its simpleprecipitation of plasm protein with acetonitrile to prepare the samples for HPLC injec |
Key words: Drug assay Monitoring therapy HPLC Amiod (on page 25) |