| 引用本文: | 周俐,上官珠,连其深,周青,曾靖;向仁德,韩英,张新勇.蛇床子素抗心律失常作用实验研究[J].中国现代应用药学,1996,(2):11-13. |
| Zhou Li, Shang-guan Zhu, Lian Qi-shen, Zhou Qing, Zeng Jing，Xiang Ren-de, Han Ying, Zhang Xin-yong.Experimental Studies on the Anti-arrhythmia Effects of Osthol[J].Chin J Mod Appl Pharm(中国现代应用药学),1996,(2):11-13. |
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| 摘要: |
| 蛇床子素(Ost)对氯仿诱发的小鼠室颤、氯化钙诱发的大鼠室颤均有明显的预防作用,对乌头碱诱发的大鼠心律失常有明显的治疗效果,且能明显提高兔心室电致颤阈.这些结果均表明Ost有抗心律失常作用,并揭示其对钠、钙通道有一定的阻断作用。 |
| 关键词: 蛇床子素 心室纤颤 心律失常 |
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| Experimental Studies on the Anti-arrhythmia Effects of Osthol |
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Zhou Li, Shang-guan Zhu, Lian Qi-shen, Zhou Qing, Zeng Jing，Xiang Ren-de, Han Ying, Zhang Xin-yong
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| Abstract: |
| Osthol (Ost ) was not only effective in preventing ventricular fiarillation indu-ed by chloroform in mice and by calcium chloride in rats, but was effective in treating arrh-ythmia illduced by aconitine in rats. Furthermore, Ost raised the threshold of ve |
| Key words: Osthol Ventricuiur fibrillation Arrhythmia |
