HPLC测定鼻可灵喷雾剂中氧氟沙星和盐酸麻黄碱的含量

吴朝晖;张守尧;张忠义;邹恒琴;邓葛峰1

引用本文:	吴朝晖;张守尧;张忠义;邹恒琴;邓葛峰1.HPLC测定鼻可灵喷雾剂中氧氟沙星和盐酸麻黄碱的含量[J].中国现代应用药学,1998,(2):54-55.
	Wu Zhaohui(Wu ZH),et al.The determination of ofloxacin and ephedrine hydrochloride in Bikeling nasal drops by HPLC[J].Chin J Mod Appl Pharm(中国现代应用药学),1998,(2):54-55.

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HPLC测定鼻可灵喷雾剂中氧氟沙星和盐酸麻黄碱的含量
吴朝晖;张守尧;张忠义;邹恒琴;邓葛峰1

作者	单位
吴朝晖;张守尧;张忠义;邹恒琴;邓葛峰1

摘要:

采用高效液相色谱法,同时测定了鼻可灵喷雾剂中氧氟沙星和盐酸麻黄碱的含量。色谱柱为Hypersil BDS(4mm×250mm),流动相为0.1%三乙胺(用磷酸调pH至3.2)-乙腈(85:15),检测波长为256nm。两被测组分的回收率分别为氧氟沙星100.2%,盐酸麻黄碱100.7%,日内、日间偏差均小于5%。

关键词: 高效液相色谱法氧氟沙星盐酸麻黄碱鼻可灵喷雾剂

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The determination of ofloxacin and ephedrine hydrochloride in Bikeling nasal drops by HPLC

Wu Zhaohui(Wu ZH),et al

Abstract:

Ofloxacin and ephedrine hydrochloride in Bikeling nasal drops were simultaneously determined by HPLC. The column was hypersil BDS(4mm x 250mm). The mobile phase was 0. 1% triethylamine(adjusted to pH 3.2 with phosphoric acid)-acetonitrile(85:15). The dete

Key words: HPLC, ofloxacin, ephedrine hydrochloride, Bikeling nasal drops