| 引用本文: | 邹霈;罗世能;谢敏浩;刘娅灵;何拥军.3,5-双(N-2,3-二羟丙基)乙酰胺基-N-(2-羟乙基)-2,4,6-三碘苯甲酰胺的合成[J].中国现代应用药学,1998,(3):33-34. |
| Zhou Pel ( Zhou P ), Luo Shineng ( Luo SN ), Xie Minghao ( Xie MH), et al.Synthesis of 3,5-bis[acetyl(2,3-dihydroxypropyl) amino]-N-(2-hydroxyethyl)-2,4,6-triiodo-benzamide[J].Chin J Mod Appl Pharm(中国现代应用药学),1998,(3):33-34. |
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| 摘要: |
| 报道了新型非离子型X-CT造影剂[3,5-双(N-2,3-二羟丙基)乙酰胺基-N-(2-羟乙基)-2,4,6-三碘苯甲酰胺]的化学合成。该化合物以苯甲酸为原料,经硝化、酯化、酰胺化、还原、碘化、酰化、烷基化等制备而成。产物经元素分析、红外光谱、核磁共振谱等测定,与结构完全一致。 |
| 关键词: CT造影剂 苯甲酰胺 合成 |
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| Synthesis of 3,5-bis[acetyl(2,3-dihydroxypropyl) amino]-N-(2-hydroxyethyl)-2,4,6-triiodo-benzamide |
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Zhou Pel ( Zhou P ), Luo Shineng ( Luo SN ), Xie Minghao ( Xie MH), et al
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| Abstract: |
| The synthesis of novel non - ionic X - CT contrast medium {3,5 - bis [ acetyl (2,3- dihydroxypropyl)amino] - N - (2 - hydroxyethyl) - 2,4,6- triiodo - benzamide} is reoported. This compound was synthesized through nitration, esterification, amidation, red |
| Key words: CT contrast medium,benzamide,synthesis |
