引用本文: | 谢云;薛大权;卢源峰;杨国江1;赖淑武1.双氯芬酸钠肠溶片质量考察[J].中国现代应用药学,1998,(3):42-43. |
| Xie Yun(Xie Y) ,Xue Daquan(Xue DQ) ,Lu Yuanfeng(Lu YF), et al.Quality studies of diclofenac sodium enteric coated tablets[J].Chin J Mod Appl Pharm(中国现代应用药学),1998,(3):42-43. |
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摘要: |
利用RP-HPLC,以卡马西平(CZ)为内标,对国内3个厂家生产的双氯芬酸钠(D5)肠溶片进行了崩解度、释放度、含量测定的研究。结果表明:不同厂家的DS肠溶片释放度差异极为显著(P<0.01)、崩解度与释放度之间有较好的相关性(r=0.9103)。 |
关键词: 双氯芬酸钠肠溶片 卡马西平 崩解度 释放度 相关性 |
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Quality studies of diclofenac sodium enteric coated tablets |
Xie Yun(Xie Y) ,Xue Daquan(Xue DQ) ,Lu Yuanfeng(Lu YF), et al
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Abstract: |
The disintegration, release rate and assay of diclofenac sodium enteric coated tablets produced by three factories(A,B,C) in our country were determined by RP - HPLC with internal standard carbamazepine.The results showed that the difference of the releas |
Key words: dicolfenac sodium enteric coated tablet, carbamzepine, disintegration, release rate, correlation |