引用本文: | 王立明;申屠建中;朱幸芳1;方瑞英.复方黄芩制剂抗大鼠肝纤维化作用[J].中国现代应用药学,1998,(4):14-16. |
| Wang Liming (Wang LM),Shentu Jianzhong (Shentu JZ),Zhu Xingfang(Zhu XF),et al.Anti-hepatofibrotic effect of compound scutellaria liquid extract in rats[J].Chin J Mod Appl Pharm(中国现代应用药学),1998,(4):14-16. |
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摘要: |
目的:研究复方黄芩制剂抗肝纤维化的作用。方法:采用皮下注射CCl4和营养控制两因素致大鼠肝纤维化模型,从组织病理学和组织化学两方面进行现察。结果:复方黄芩制剂ig给药,5~10g/kg能明显减轻大鼠纤维化程度(P<0.01)。结论:复方黄苓制剂具有显著的抗肝纤维化作用。 |
关键词: 复方黄芩制剂 联苯双酯 肝纤维化 四氯化碳 |
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基金项目:浙江省自然科学基金资助项目第394210号 |
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Anti-hepatofibrotic effect of compound scutellaria liquid extract in rats |
Wang Liming (Wang LM),Shentu Jianzhong (Shentu JZ),Zhu Xingfang(Zhu XF),et al
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Abstract: |
OBJECTIVE: To study the anti-hepatofibrotic effects of compound scutellaria liquid extract (CSLE). METHODS:Hepatic fibrosis model was induced by CCl4 and nutrition restriction in rats. The severity of fibrosis was assessed with histopathological and histo |
Key words: compoud scutellaria liquid extract, biphenyldicarboxylate, hepatic fibrosis, CCl4 |