| 引用本文: | 许东航;梁文权1;宋继芬.盐酸丁卡因离子导入研究[J].中国现代应用药学,1999,(3):26-27. |
| Xu Donghang(Xu DH),Liang Wenquan(Liang WQ),Song Jifen(Song JF).Study of iontophoresis of dicaine hydrochloride[J].Chin J Mod Appl Pharm(中国现代应用药学),1999,(3):26-27. |
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| 摘要: |
| 目的:研究药物的电压与离子导入速率的关系。方法:以盐酸丁卡因为模型药物,采用去毛大鼠腹部皮肤和双室扩散池,分别测定不同电压下的增渗倍数(ER)。结果:增渗倍数对电压的线性回归方程为:ER =-3×10-3+3.202V ,r=0 .9979。结论:增渗倍数与电压成正比 |
| 关键词: 离子导入 电压 增渗倍数 盐酸丁卡因 |
| DOI： |
| 分类号: |
| 基金项目:国家自然科学基金项目!第 39370658号 |
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| Study of iontophoresis of dicaine hydrochloride |
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Xu Donghang(Xu DH),Liang Wenquan(Liang WQ),Song Jifen(Song JF)
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| Abstract: |
| OBJECTIVE:To study the effect of voltage on drug transdermal iontophoresis.METHOD:The enhancing rate(ER) of dicaine hydrochloride with different voltage through rat skin were determined respectively using valia-chien two-chamber diffusion cells.RESULTS:li |
| Key words: iontophoresis,voltage,enhancing rate,dicaine hydrochloride |
