| 引用本文: | 郑青山;桂常青1;孙瑞元1.阿司匹林、布他比妥和咖啡因联用对小鼠的镇痛作用及其急性毒性的定量分析[J].中国现代应用药学,2000,(2):93-97. |
| Zheng Qingshan(Zheng QS),Gui Changqing(Gui CQ),Sun Ruiyuan(Sun RY).Quantitative analysis of analgesic effect and acute toxicity of aspirin,butabital and caffeine in combination to mice[J].Chin J Mod Appl Pharm(中国现代应用药学),2000,(2):93-97. |
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| 关键词: 阿司匹林 布他比妥 咖啡因 均匀设计 药物联合治疗 药物协同作用 药物拮抗作用 药物相互作用 |
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| 基金项目:国家自然科学基金!(39670845);;安徽省自然科学基金!(9845 4735);;卫生部科研基金!(94-1-335)资助 |
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| Quantitative analysis of analgesic effect and acute toxicity of aspirin,butabital and caffeine in combination to mice |
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Zheng Qingshan(Zheng QS),Gui Changqing(Gui CQ),Sun Ruiyuan(Sun RY)
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| Abstract: |
| OBJECTIVE:To analyzed quantitatively the analgesic effect and acute toxicity of aspirin(Asp),butabital(But) and caffeine(Caf) in combination with the method of the formula uniform design and study the feasibility of this method to analyze multidrug effect |
| Key words: aspirin,butabital,caffeine,combination drug therapy,drug synergism,drug antagonism,drug interactions |
