| 引用本文: | 周莉玲;刘强1;李锐.青藤碱贴片经皮渗透的比较研究[J].中国现代应用药学,2000,(3):200-202. |
| Zhou Liling(Zhou LL),Liu Qiang(Liu Q),Li Rui(Li R).Study of tramsdermal drug delivery system of sinomenine[J].Chin J Mod Appl Pharm(中国现代应用药学),2000,(3):200-202. |
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| 摘要: |
| 目的:对比研究4种青藤碱贴片的经皮渗透行为。方法:以pH 6.8磷酸缓冲液为接收液,以裸鼠皮肤为实验材料,对比研究了4种青藤碱TDD制剂的经皮渗透行为。结果:4种TDD制剂中,以TDD4的透皮速率常数为最高,以TDD3为最低。结论:空白压敏胶对药物从贮库向皮肤转运有一定程度的阻滞作用。 |
| 关键词: 青藤碱 贴片 比较研究 |
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| 基金项目:国家中医药管理局科研基金课题!课题编号 95B131 |
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| Study of tramsdermal drug delivery system of sinomenine |
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Zhou Liling(Zhou LL),Liu Qiang(Liu Q),Li Rui(Li R)
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| Abstract: |
| OBJECTIVE:To compare the transdermal profile of 4 types of sinomenine TDD.METHOD:The transdermal profile of 4 types of sinomenine TDD were studied comparatively on hareless mice skin with phosphate buffer(pH6.8) as the absorption solution.RESULTS:Among th |
| Key words: sinomenine,TDDs,comparative |
