| 引用本文: | 孟昭力;唐龙骞;赵彦伟;王德凤.巴柳氮(Balsalazide)的合成[J].中国现代应用药学,2000,(6):465-466. |
| Meng ZHaoli(Meng ZL),Tang Longqian(Tang LQ),Zhao Yanwei(Zhao YW),et al.Synthesis of Balsalazide[J].Chin J Mod Appl Pharm(中国现代应用药学),2000,(6):465-466. |
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| 摘要: |
| 目的:合成巴柳氮并进行工艺改进。方法:以对 硝基苯甲酰氯为原料,经氨解、氢化、重氮化及偶合四步反应得到了巴柳氮。结果:所得产物经元素分析、红外光谱确证其结构。结论:采用此法合成巴柳氮是可行的,并提高了反应收率 |
| 关键词: 巴柳氮 合成 |
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| Synthesis of Balsalazide |
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Meng ZHaoli(Meng ZL),Tang Longqian(Tang LQ),Zhao Yanwei(Zhao YW),et al
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| Abstract: |
| OBJECTIVE:To synthesize balsalazide and optimize the process.METHODS:This compound was synthesize by steps of ammonolysis,hydrogenize,diazotization and coupling from 4-nitrobenzoyl chloride.RESULTS:Chemical structure of the product was confirmed by elemen |
| Key words: balsalazide,synthesis |
