引用本文: | 谢奇峰;唐细兰;宋湘芝;赵志新.反相高效液相色谱法测定血浆中两性霉素B浓度[J].中国现代应用药学,2001,(2):126-128. |
| Xie Qifeng(Xie QF),Tang Xilan(Tang XL),Song Xiangzhi(Song x2H etal.Determination of amphotericin B in human plasma by reversed-phase HPLC[J].Chin J Mod Appl Pharm(中国现代应用药学),2001,(2):126-128. |
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摘要: |
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关键词: 两性霉素B 高效液相色谱法 血药浓度 |
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基金项目:广东省科委重点攻关资助项目! (9737) |
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Determination of amphotericin B in human plasma by reversed-phase HPLC |
Xie Qifeng(Xie QF),Tang Xilan(Tang XL),Song Xiangzhi(Song x2H etal
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Abstract: |
OBJECTIVE:To establish a reversed-phase HPLC assay to monitor the plasma concentration of Amphotericin B.METHOD:Amphotericin B was separated on ODS-Hypersil C18 column and detected at UV380nm,using 0.005mol/L EDTA-2Na-methanol(2:8,v/v) as mobile phase,and |
Key words: HPLC,anphotericin B,Plasma concentration |