| 引用本文: | 汪凤梅;姚彤炜;吴越1;曾苏2.HPLC测定人肝转基因细胞中的盐酸维拉帕米[J].中国现代应用药学,2001,(5):379-381. |
| Wang Feng Mei ,Yao Tong Wei,Wu Yue 1, Zeng Su 2.Determination of Verapamil Metabolism in cDNA-expressed cells by HPLC[J].Chin J Mod Appl Pharm(中国现代应用药学),2001,(5):379-381. |
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| 摘要: |
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| 关键词: 维拉帕米 反相高效液相色谱 细胞色素P450转基因细胞 孵育 |
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| 基金项目:国家自然科学基金 ( No 39370805) ;Tel:(0571)87217203;E-mail:zengsu@yahoo.com |
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| Determination of Verapamil Metabolism in cDNA-expressed cells by HPLC |
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Wang Feng Mei ,Yao Tong Wei,Wu Yue 1, Zeng Su 2
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| Abstract: |
| OBJECTIVE:To establish a RP HPLC method for the determination of verapamil after metabolism by cytochrome P450 cDNA transgenic cell homogenate. METHOD:The determination was performed on a C18 reversed phase column with a mobile phase composed of methano |
| Key words: Verapamil, RP HPLC ,Cytochrome p450 cDNA transgenic cell, Incubation |
