| 引用本文: | 吴道澄;马保安1;万明习;范清宇1.MDP-阿霉素脂质体交联物治疗大鼠成骨肉瘤的药效学研究[J].中国现代应用药学,2002,(6):435-437. |
| Wu Daocheng(Wu DC), Ma Baoan 1(Ma BA), Wan Mingxi(Wan MX), Fan Qingyu 1 (Fan QY).Study on the pharmacodynamics of the adriamycin liposome conjugated MDP on UMR 106 osteosarcoma tumor model[J].Chin J Mod Appl Pharm(中国现代应用药学),2002,(6):435-437. |
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| 关键词: 阿霉素脂质体 药效学 成骨肉瘤 亚锡亚甲基二膦酸 高效液相色谱 |
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| Study on the pharmacodynamics of the adriamycin liposome conjugated MDP on UMR 106 osteosarcoma tumor model |
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Wu Daocheng(Wu DC), Ma Baoan 1(Ma BA), Wan Mingxi(Wan MX), Fan Qingyu 1 (Fan QY)
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| Abstract: |
| OBJECTIVE:To prepare adriamycin liposome conjugated with MDP (Methylenediphonate,MDP LADM) and observe its therapeutic effect on UMR106 osteosarcoma tumor model in rat, as well as comparing it with adriamycin liposome (LADM) and free adriamycin(ADM) . ME |
| Key words: adriamycin liposome, pharmacodynamics, osteosarcoma tumor, MDP, HPLC |
