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关键词: 安替比林 肉豆蔻酸异丙酯 剥离角质层 经皮吸收 |
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Influence of different skin tissue on the percutaneous absorption of antipyrine patch |
LI Guo-feng 1, XING Xiao-hui 2
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Abstract: |
OBJECTIVE To investigate the influence of skin layers (stratum corneum and viable layer) on the percutaneous absorption of drug with or without isopropyl myristate (IPM). METHOD We chose antipyrine (AT) as a model drug. Patches containing saturated conc |
Key words: antipyrine isopropyl myristate stratum corneum stripped skin in vitro percutaneous absorption |