引用本文: | 周燕文1;李梅1;晏秋宁2;雷宇2.口服氢氧化铝对静脉给予环丙沙星的体内药动学影响[J].中国现代应用药学,2003,(1):33-35. |
| ZHOU Yan-wen 1, LI Mei 1, YAN Qiu-ning 2, LEI Yu 2.Effect of oral administration of aluminum hydroxide on the pharmacokinetics of intravenous ciprofloxacin in Rabbits[J].Chin J Mod Appl Pharm(中国现代应用药学),2003,(1):33-35. |
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关键词: 环丙沙星 氢氧化铝 相互作用 药动学参数 血药浓度 |
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Effect of oral administration of aluminum hydroxide on the pharmacokinetics of intravenous ciprofloxacin in Rabbits |
ZHOU Yan-wen 1, LI Mei 1, YAN Qiu-ning 2, LEI Yu 2
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Abstract: |
OBJECTIVE To evaluate the reasonability of oral aluminum antiacid concurrently with intravenous ciprofloxacin injection in rabbits. METHOD Eight normal rabbits received intravenous ciprofloxacin injection with and without oral aluminum hydroxide suspent |
Key words: ciprofloxacin aluminum hydroxide interaction pharmacokinetics serum drug concentration |