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| 关键词: 雷洛昔芬 合成 |
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| Synthesis of raloxifene hydrochloride |
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JIA Wei-ru, ZHANG Jing
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| Abstract: |
| OBJECTIVE To Synthesize Raloxifene Hydrochloride. METHOD Raloxifene was synthesized by cyclizing and demethoxylating of 3 methoxybenzenethiol, then treated with 4-[2-(1-pyrroldinyl)ethoxy]benzoyl chloride in the presence of monothioglycol to give Ralox |
| Key words: raloxifene hydrochloride, synthesis |
