| 引用本文: | 胡全1,2;魏尔清1;章征1;朱朝阳1.白三烯拮抗剂ONO-1078的一般神经药理特点[J].中国现代应用药学,2003,(4):259-262. |
| HU Quan 1, 2 , WEI Er-qing 1, ZHANG Zheng 1,ZHU Chao-yang.Neuropharmacological properties of ONO-1078,a leukotriene antagonist in mice[J].Chin J Mod Appl Pharm(中国现代应用药学),2003,(4):259-262. |
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| 摘要: |
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| 关键词: ONO-1078 自发活动 行为学作用 学习记忆 镇痛 |
| DOI： |
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| 基金项目:国家自然科学基金项目 (No .39770270) |
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| Neuropharmacological properties of ONO-1078,a leukotriene antagonist in mice |
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HU Quan 1, 2 , WEI Er-qing 1, ZHANG Zheng 1,ZHU Chao-yang
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| Abstract: |
| OBJECTIVE ONO-1078, a leukotriene antagonist, has neuroprotective effect on brain ischemia. This study aims to determine the effects of ONO-1078 on central nervous system to evaluate its safety in mice. METHOD Spontaneous locomotor test, neuromuscular a |
| Key words: {pranlukast,4-oxo-8-[ p-(4-phenylbutyloxy) benzoyl amino]-2-(tetrazol-5-yl)-4H-1-benzopyran hemihydrate} spontaneous locomotor activity behavioral activity, learning and memory analgesia |
