引用本文: | 张红梅1;李长龄1;李润涛2.1,6-二(4-苯乙基-1-甲基-1-哌嗪基)己烷二溴化物镇痛作用及机制探讨[J].中国现代应用药学,2003,(6):439-441. |
| ZHANG Hong-mei 1, LI Chang-ling 1 , LI Run-tao 2.Analgesic effects and mechanisms of 1,6-Di-(4-phenethyl-1-methyl-1-piperazinyl) hexane dibromide[J].Chin J Mod Appl Pharm(中国现代应用药学),2003,(6):439-441. |
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关键词: 哌嗪类 1,6-二(4-苯乙基-1-甲基-1-哌嗪基)己烷二溴化物 镇痛 纳洛酮 |
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基金项目:国家自然科学基金项目 (29972005) |
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Analgesic effects and mechanisms of 1,6-Di-(4-phenethyl-1-methyl-1-piperazinyl) hexane dibromide |
ZHANG Hong-mei 1, LI Chang-ling 1 , LI Run-tao 2
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Abstract: |
OBJECTIVE To investigate the analgesic effects and mechanisms of 1,6-Di-(4-phenethyl-1-methyl-1-piperazinyl)hexane dibromide (97-9-G4). METHOD The writhing model of mice induced by acetic acid and hot plate test (sc, icv) were used to study the analges |
Key words: piperazines 1,6-Di (4-phenethyl-1-methyl-1-piperazinyl)hexane dibromide analgesia naloxone |