引用本文: | 马仁玲1;周红华1;严玲3;濮社班2;盛龙生1.高效液相色谱-质谱联用法测定人血浆中奥昔布宁的浓度[J].中国现代应用药学,2003,(6):479-481. |
| MA Ren-ling 1, ZHOU Hong-hua 1,PU She-ban 2,SHENG Long-sheng 1.Determination of oxybutynin in human plasma by HPLC-MS[J].Chin J Mod Appl Pharm(中国现代应用药学),2003,(6):479-481. |
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关键词: 高效液相色谱质谱联用 奥昔布宁 药代动力学 |
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Determination of oxybutynin in human plasma by HPLC-MS |
MA Ren-ling 1, ZHOU Hong-hua 1,PU She-ban 2,SHENG Long-sheng 1
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Abstract: |
OBJECTIVE To develop a HPLC ESI MS method for determination of oxybutynin in human plasma. METHOD The mobile phase was composed of 0.01mol/L ammonium acetate/water: methanol(15:85),phenoprolamine hydrochloride was used as internal standard. Plasma sam |
Key words: HPLC MS oxybutynin pharmacokinetics |