引用本文: | 莫志贤1;梁荣能2;王彩云1.青风藤及青藤碱对吗啡依赖小鼠位置偏爱效应及cAMP水平的影响[J].中国现代应用药学,2004,(2):87-90. |
| MO Zhi-xian 1,LIANG Rong-neng 2,WANG Cai-yun 1.Effects of Caulis Sinomenii and sinomenine on morphine-induced place preference and cyclic AMP level in mice[J].Chin J Mod Appl Pharm(中国现代应用药学),2004,(2):87-90. |
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关键词: 青风藤 青藤碱 吗啡 条件性位置偏爱 cAMP 精神依赖 |
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基金项目:国家自然科学基金资助项目 (30271610) |
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Effects of Caulis Sinomenii and sinomenine on morphine-induced place preference and cyclic AMP level in mice |
MO Zhi-xian 1,LIANG Rong-neng 2,WANG Cai-yun 1
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Abstract: |
OBJECTIVE To explore the effects of Caulis Sinomenii and sinomenine on the conditioned place preference induced by morphine in mice and its relation to cAMP level of the brain. METHOD Morphine was injected (9mg/kg, one time/day,sc) to mice for 5days. T |
Key words: Caulis Sinomenii sinomenine morphine conditioned place preference cyclic AMP psychic dependence |