引用本文: | 李芹1;陈建中2;郭瑞臣3.奥硝唑血药浓度的高效液相色谱法测定及其国产和进口片剂的药动学和生物等效性研究(英文)[J].中国现代应用药学,2004,(2):129-132. |
| LI Qin 1, CHEN Jian-zhong 2, GUO Rui-chen 3.Determination of ornidazole in plasma by HPLC and study on its pharmacokinetics and bioequivalence of domestic and imported tablets in 18 healthy volunteers[J].Chin J Mod Appl Pharm(中国现代应用药学),2004,(2):129-132. |
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关键词: 奥硝唑 高效液相色谱法 药动学 生物等效性 |
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Determination of ornidazole in plasma by HPLC and study on its pharmacokinetics and bioequivalence of domestic and imported tablets in 18 healthy volunteers |
LI Qin 1, CHEN Jian-zhong 2, GUO Rui-chen 3
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Abstract: |
OBJECTIVE To establish a reversed HPLC method for the determination of ornidazole in human plasma, and study the pharmacokinetics and bioequivalence of domestic and imported tablets in healthy volunteers.METHOD The drug was extracted from plasma with me |
Key words: ornidazole HPLC pharmacokinetics bioequivalence |