| 引用本文: | 许东航，梁文昌，周宏民.特非那定片溶出度测定[J].中国现代应用药学,2004,(7):47-49. |
| Xu Dong-hang*, Leong Man-cheong, Zhou Hong-min.Determination Dissolution of six commercial terfenadine tablets[J].Chin J Mod Appl Pharm(中国现代应用药学),2004,(7):47-49. |
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| 摘要: |
| 目的评价市场上6个批号的特非那定片的质量。方法采用桨法作为溶出度测定法，HPLC作为特非那定浓度测定方法，再通过weibull's方程获得溶出度参数。结果仅有2个批号的特非那定片达到卫生部部颁标准。结论我们应该关注市场上特非那定片的质量。 |
| 关键词: 特非那定 溶出度 高效液相色谱法 |
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| Determination Dissolution of six commercial terfenadine tablets |
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Xu Dong-hang*, Leong Man-cheong, Zhou Hong-min
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| Abstract: |
| OBJECTIVETo evaluate the drug quality in vitro of six commercial terfenadine tablets. METHODThe initial dissolution rate were measured using rotating paddle method. HPLC-method was used to determine the concentration of terfenadine and the Weibull's equat |
| Key words: terfenadine dissolution HPLC |
