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摘要: |
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关键词: 药动学 Excel软件 米氏消除 龙格库塔算法 静脉滴注 |
DOI: |
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基金项目:温州市科技局资助项目(Y2003A075) |
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A Numerical method for plasma concentration of drugs obeying pa rallel first order and Michaelis-Menten clearance kinetics by intravenous infus ion administration based on Runge-Kutta algorithm and Microsoft Excel software |
SU Yin-fa
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Abstract: |
OBJECTIVE To obtain a numerical method f or the plasma concentration of drugs obeying parallel first and Michaelis-Menten clearance kinetics by intravenous infusion administration.METHOD Microsoft Excel was used to write a Microsoft Excel spre adsheet |
Key words: pharmacokinetics Excel software Michaelis-Menten c learance Runge-Kutta algorithm intravenous infusion administration |