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摘要: |
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关键词: 非线性回归 SPSS 药动学参数 拟合 血管外给药 |
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Estimating the pharmacokinetic parameters in extravascular administration by SPSS |
MO Zhi-jiang
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Abstract: |
OBJECTIVE To estimate the pharmacokinetic parameters of compartment models with extravascular administration using SPSS.METHOD Concentration-time data from the simulation of two-compartment model with the 1st order absorption and lag time( tlag ) were fit |
Key words: nonlinear regression SPSS pharmacokinetic parameters fit extravascular administration |