| 引用本文: | 杨伟峰1;马张英2;罗金文1.液相色谱-串联质谱法测定人血浆中劳拉西泮的浓度及其在生物等效性研究中的应用[J].中国现代应用药学,2005,(4):318-321. |
| YANG Wei-feng~1,MA Zhang-ying~2,LUO Jin-wen~1.Determination of lorazepam in plasma by LC/MS/MS and its application in the bioequivalence study[J].Chin J Mod Appl Pharm(中国现代应用药学),2005,(4):318-321. |
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| 关键词: 劳拉西泮 液相色谱-串联质谱法 生物等效性 |
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| Determination of lorazepam in plasma by LC/MS/MS and its application in the bioequivalence study |
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YANG Wei-feng~1,MA Zhang-ying~2,LUO Jin-wen~1
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| Abstract: |
| OBJECTIVE To establish a LC/MS/MS method for determination of lorazepam in plasma and to study its bioequivalence. METHODS 0.3mL of the plasma sample was pipetted into a conical tube, 0.6mL internal standard solution containing diazepam in acetonitrile wa |
| Key words: lorazepam liquid chromatography-tandem mass spectrometry bioequivalence |
