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摘要: |
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关键词: 手性药物 扁桃酸 发酵液 分离 纯化 |
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基金项目:福建省科技厅重点(2003H023)、福建省计委(闽计46号)和福州大学SRTP(03166)资助项目。 |
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Separation and purification of chiral drugs mandelic acid from ferment broth |
LI Guo-ping1,CHEN Jian-feng1*,GUO Yang-hao1,BI Ming-bo1,XIAO Mei-tian2,HUAN Ya-yan2
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Abstract: |
OBJECTIVETo study a new method for the separation and purification of chiral drugs mandelic acid from ferment broth.METHODSThe ionization constant of mandelic acid was mensurated by pH potentiometer titration.The solubility curves of mandelic acid in diff |
Key words: chiral drugs mandelic acid ferment broth separation purification |