| 引用本文: | 严方1;杨劲2;赵陆华1;吴孟华1;谭喜莹1;潘娟1.罗红霉素胶囊人体药物动力学及生物等效性研究[J].中国现代应用药学,2006,(5):374-377. |
| YAN Fang~(1),YANG Jin~(2),ZHAO Lu-hua~(1),WU Meng-hua~(1), TAN Xi-ying~(1),PAN Juan~(1).Study of pharmacokinetics and relative bioavalability of roxithromycin[J].Chin J Mod Appl Pharm(中国现代应用药学),2006,(5):374-377. |
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| 摘要: |
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| 关键词: 罗红霉素 HPLC/MS 药物动力学 相对生物利用度 |
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| Study of pharmacokinetics and relative bioavalability of roxithromycin |
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YAN Fang~(1),YANG Jin~(2),ZHAO Lu-hua~(1),WU Meng-hua~(1), TAN Xi-ying~(1),PAN Juan~(1)
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| Abstract: |
| OBJECTIVE An HPLC-MS method was developed for determination of roxithromycin in human plasma to study the pharmacokinetic parameters in capsule and relative bioavailability.METHODS The plasma was added acetonitrile,vortexed and centrifuged. And the supern |
| Key words: roxithromycin HPLC/MS pharmacokinetics relative bioavailability |
