引用本文: | 彭文兴;朱荣华;刘晓磊;顾平.非那雄胺片的健康人体药动学研究[J].中国现代应用药学,2006,(6):449-451. |
| PENG Wen-xing,ZHU Rong-hua,LIU Xiao-lei,GU Ping.Determination of finasteride by HPLC-MS and study its pharmacokinetics[J].Chin J Mod Appl Pharm(中国现代应用药学),2006,(6):449-451. |
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关键词: 非那雄胺 HPLC-MS法 药物动力学 |
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Determination of finasteride by HPLC-MS and study its pharmacokinetics |
PENG Wen-xing,ZHU Rong-hua,LIU Xiao-lei,GU Ping
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Abstract: |
OBJECTIVE To develop a sensitive and specific HPLC-MS method for determination of finasteride in plasma,and study the pharmacokinetics in 18 healthy volunteers after oral administration of 5mg finasteride tablet.METHODS Blood samples could be well purifie |
Key words: finasteride HPLC-MS pharmacokinetics |