高效液相色谱法测定人血浆中头孢吡肟浓度及其药动学

胡婕慧1;谢林1;肖大为2;樊宏伟2;汪瑞芳;2钱薇2;刘晓东1

引用本文:	胡婕慧1;谢林1;肖大为2;樊宏伟2;汪瑞芳;2钱薇2;刘晓东1.高效液相色谱法测定人血浆中头孢吡肟浓度及其药动学[J].中国现代应用药学,2007,(1):53-56.
	HU Jie-hui1,XIE Lin1,XIAO Da-wei2,FAN Hong-wei2,WANG Rui-fang2,QIAN Wei2,LIU Xiao-dong1.HPLC Method for the Determination of Cefepime in Human Plasma and its Pharmacokinetics[J].Chin J Mod Appl Pharm(中国现代应用药学),2007,(1):53-56.

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高效液相色谱法测定人血浆中头孢吡肟浓度及其药动学
胡婕慧1;谢林1;肖大为2;樊宏伟2;汪瑞芳;2钱薇2;刘晓东1

作者	单位
胡婕慧1;谢林1;肖大为2;樊宏伟2;汪瑞芳;2钱薇2;刘晓东1

摘要:

关键词: 头孢吡肟高效液相色谱药动学

DOI：

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基金项目:

HPLC Method for the Determination of Cefepime in Human Plasma and its Pharmacokinetics

HU Jie-hui1,XIE Lin1,XIAO Da-wei2,FAN Hong-wei2,WANG Rui-fang2,QIAN Wei2,LIU Xiao-dong1

Abstract:

OBJECTIVE To develop an HPLC method with ultraviolet detection for determining cefepime in human plasma and study pharmacokinetic behavior of cefepime following intravenous administration.METHODS 12 healthy subjects received 500 mg of cefepime hydrochlori

Key words: Cefepime HPLC Pharmacokinetics