抗感染药物不良反应159例分析

The Analysis of 159 Cases about the Adverse Drug Reactions of Anti-infection Medicine

关键词:  抗感染药物  药物不良反应  分析

Key words:  anti-infection medicine  adverse drug reactions  analyze

摘要:

目的分析我院近几年来抗感染药物不良反应(ADR)的发生情况,为临床安全、合理用药提供参考。方法对我院1999年1月～2007年10月ADR监测小组收集的159例抗感染药物ADR报告进行回顾性分类统计分析。结果159例ADR报告涉及药物12类41个品种,其中喹诺酮类药物报告例数为首位,其次为林可霉素类及青霉素类药物等。ADR的临床表现主要为皮肤及其附件损害最为多见,其次为消化系统损害和神经系统损害等。结论合理使用抗感染药物,重视ADR的监测工作,减少ADR发生。

Abstract:

OBJECTIVE This paper analyzes the occurrence situation incident about the adverse drug reactions (ADR) of anti-infection medicine which happened in our hospital in recent years, and give the reference for clinical security and the rational use of medicine. METHODS With the 159 ARD reports on anti-medicine that the ADR observation group collected from January 1999 to October 2007,this passage made the retrospective statistical analysis on these data. RESULTS159 ADR reports involves the 12 kinds of medicine which include 41 varieties. On the top of these is the quinolones, and the medicines like the lincomycin and the penicillin is the next. Clinical manifestation of ARD are mainly the harm of skin and its accessory, the secondary are digestive system′s and nervous system′s. CONCLUSIONWe should use the anti-infection medicine rationally, pay attention to the observation of ADR, and then avert the accident of ADR.