今幸胶囊抗疲劳作用的实验研究

Studies on the Effects of Jinxing Capsules on the Action of Anti-fatigue

关键词:  今幸胶囊  抗疲劳试验  小鼠

Key words:  Jinxing capsules  anti-fatigue  mice

摘要:

目的评价今幸胶囊对小鼠的抗疲劳作用效果。方法选用昆明种小鼠， 按高、中、低3个剂量组、1个正常对照组和1个阳性对照组随机分组，分别观察小鼠游泳试验结果并测定生化指标(血清尿素氮、乳酸、肝糖原)。结果受试物组小鼠与正常对照组各观察指标相比,负重游泳时间延长； 血中尿素氮水平、乳酸含量降低，且均以中、高剂量组与之差异明显(P<0.05)；肝糖原含量升高，以高剂量组差异明显(P<0.05)，说明生化指标的改变与抗疲劳试验的结果相符。结论今幸胶囊具有明显的抗疲劳作用。

Abstract:

OBJECTIVE To evaluate the effects of Jinxing capsule on the action of anti-fatigue.METHODS Kunming mice were randomly divided into five groups,the low,middle and high dosage groups,normal control group as well as the treatment group.All the mice were experimented with swimming test and their various biochemistry indexes were observed. RESULTS All tested groups survived longer than the normal control during swimming test. There was significant difference among the high,middle dosage and the normal control(P<0.05) .The serum urea nitrogen and lactic acid of all tested groups were lower than that of the normal control.There was significant difference among the high,middle dosage and the normal control(P<0. 05).The hepatic glycogen of all tested groups was higher than that of the normal control.There was significant difference between the high dosage and the normal control(P<0.05 ).CONCLUSION Jinxing capsule is efficient on the action of anti-fatigue.