| 引用本文: | 徐艳丽1，吴玉波1，姜同英2*.HPLC测定宁嗽露(糖浆剂)中盐酸麻黄碱的含量[J].中国现代应用药学,2009,(9):770-772. |
| XU Yanli1, WU Yubo1, JIANG Tongying2*.Determination of Ephedrine Hydrochlorid in Ninsoulu(Syrup) by HPLC[J].Chin J Mod Appl Pharm(中国现代应用药学),2009,(9):770-772. |
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| 摘要: |
| 目的 建立以高效液相色谱法测定宁嗽露(糖浆剂)中盐酸麻黄碱含量的方法。方法 色谱柱为Diamonsil Ｃ18柱(250 mm×4.6 mm，5 μm)，流动相为乙腈-0.1％磷酸液(9∶91)，检测波长为207 nm。结果 盐酸麻黄碱线性范围为1.026～102.6 mg · mL-1(r=0.999 8)，平均回收率为99.02% (RSD=1.12%)。结论 本方法简便、准确、重复性好，可用于测定宁嗽露(糖浆剂)中盐酸麻黄碱的含量。 |
| 关键词: 高效液相色谱法 宁嗽露(糖浆剂) 盐酸麻黄碱 含量测定 |
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| Determination of Ephedrine Hydrochlorid in Ninsoulu(Syrup) by HPLC |
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XU Yanli1, WU Yubo1, JIANG Tongying2*
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| Abstract: |
| OBJECTIVE To determine the (250 mm×4.6 mm, 5 μm) content of ephedrine hydrochlorid in Ningsoulu (syrup) by HPLC. METHODS The stationary phase was Diamonsil C18 column and the mobile phase was acetonitrile-0.1% phosphoric acid solution(9∶91), and the wavelength was set at 207 nm. RESULTS The linear range of ephedrine hydrochlorid was 1.026-102.6 mg·mL-1(r =0.999 8) with an average recovery rate was 99.02% (RSD=1.12%). CONCLUSIONS The method was simple, accurate and reproduciable, and it can be applied to determine the content of ephedrine hydrochlorid in Ningsoulu(syrup). |
| Key words: HPLC ningsoulu (syrup) ephedrine hydrochlorid content deternation |
