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引用本文:胡宗礼,黄晓萍,陈珺霞.冠心康片总黄酮含量的测定[J].中国现代应用药学,2009,(13):1161-1162.
HU Zongli,HUANG Xiaoping,CHEN Junxia.Determination of Total Flavonoids Contents from Guanxinkang Tablet[J].Chin J Mod Appl Pharm(中国现代应用药学),2009,(13):1161-1162.
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冠心康片总黄酮含量的测定
胡宗礼,黄晓萍,陈珺霞
作者单位
胡宗礼,黄晓萍,陈珺霞  
摘要:
目的采用分光光度法测定冠心康片中总黄酮的含量。方法以芦丁为标准品建立标准曲线,检测波长为510 nm。结果回归方程为C=-0.001 42 + 0.855 8A,在0.075 1~0.600 4 mg内呈良好线性关系(r=0.999 9),平均加样回收率为99.42%,RSD为1.64%(n=5)。不同批号冠心康片每片总黄酮平均含量为0.363 1 mg。结论该方法简便、准确,适用于冠心康片的质量分析检验。
关键词:  冠心康片  总黄酮  分光光度法
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Determination of Total Flavonoids Contents from Guanxinkang Tablet
HU Zongli,HUANG Xiaoping,CHEN Junxia
Abstract:
OBJECTIVE To determine the contents of total flavonoids in Guanxinkang tablet by spectrophotometry.METHODS Taking rutin as the control to make standard curve,the detective wavelength was 510 nm.RESULTS Regression equation was C=-0.001 42+0.855 8A(r=0.999 9).The linear concentration was in the range of 0.075 1-0.600 4 mg for rutin.The average recovery was 99.42%,RSD was 1.64%(n=5).The average contents of total flavonoids from Guanxinkang tablet with different numbers was 0.363 1 mg.CONCLUSION The method is simple and accurate,it can be used for quality control of Guanxinkang tablet.
Key words:  Guanxinkang tablet  spectrophotometry  total flavonoids
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