我院万古霉素使用情况分析

Analysis of the Clinical Application of Vancomycin Use in Our Hospital

关键词:  万古霉素  血药浓度监测  葡萄球菌

Key words:  vancomycin  monitoring of drug concentration in blood  staphylococcus

摘要:

目的 评价我院33例万古霉素临床应用情况。方法 对本院2008年1月－2009年1月使用万古霉素并同时进行血药浓度监测的33例病例进行回顾性统计分析。结果 33例中，万古霉素的临床治疗有效率为57.58％，药物利用指数DUI为0.609。结论 我院万古霉素使用情况基本合理。万古霉素治疗窗窄，临床上使用万古霉素应进行血药浓度监测。

Abstract:

OBJECTVE To evaluate the clinical application of vancomycin use in 33 cases in our hospital. METHODS The 33 cases of patients who took vancomycin while their drug concentration in blood was monitored between Jan 2008 and Jan 2009 were reviewed and analyzed statistically. RESULTS In the 33 cases, the efficiency of clinical treatment was 57.58％, and the drug utilization index(DUI) was 0.609. CONCLUSION The use of vancomycin in our hospital was rational in general. The vancomycin concentration in blood should be monitored meanwhile because of the narrow therapeutic window of vancomycin.