丹参注射液临床应用安全性的初步评价

Preliminary Safety Evaluation of Salvia Miltiorrhiza Injection in Its Clinical Application

关键词:  丹参注射液  临床应用  合理用药  安全性

Key words:  Salvia Miltiorrhiza injection  clinical application  rational drug use  safety

摘要:

目的 初步评价丹参注射液的临床应用安全性。方法 调查统计粤北人民医院2008年4月—12月所有使用过丹参注射液的住院患者病例，并分析其用药情况。结果 共收集使用过丹参注射液的住院患者病例968例，调查结果涉及19个科，30余种病种。发生ADR有12例，占1.2 %。其中按说明书规定的适应症、用法用量使用不良反应发生率最低。结论 严格按照药品说明书的规定使用有利于提高其临床应用的安全性。

Abstract:

OBJECTIVE To generally evaluate the clinical security of the Salvia Miltiorrhiza injection. METHODS Collect statistics and research on the inpatient cases of Salvia Miltiorrhiza injection in people’s hospital of Yuebei during the period of April and December 2008. RESULTS Based on the 968 inpatient cases of SMI collected which involved 19 departments and 30-odd diseases, whilst ADR occurred in 12 cases (1.2% among the total). The rate of negative-effect was utmost reduced when the applications followed the instructions of symptom, procedure and dosage. CONCLUSION The security of clinical application of SMI would be enhanced by accurate operations that are strictly in line with the instructions of treatment.