围手术期预防用抗菌药物合理应用敏感指标构建

Establishment of Sensitive Indexes of Rational Application of Perioperative Prophylactic Use of Antibiotics

关键词:  预防性用药  抗菌药物  围手术期  敏感指标  德尔菲专家函询法

Key words:  prophylactic medication  antibiotics  perioperative period  sensitive indexes  Delphi method

摘要:

目的 构建围手术期预防用抗菌药物合理应用敏感指标。方法 通过循证初步建立围手术期预防用抗菌药物合理应用敏感指标，再通过德尔菲专家函询法，对药学和医学人员共36名进行2轮函询，并统计整理函询结果。结果 构建的围手术期预防用抗菌药物合理应用敏感指标包括1级指标3项，2级指标9项和3级指标16项。2轮专家函询有效回收率分别为90%和100%。第2轮权威系数为0.83，总体协调系数0.370，检验具有统计学意义（P<0.01）。结论 本研究构建的围手术期预防用抗菌药物合理应用敏感指标满足专家积极程度、权威程度和一致性标准等各项标准，值得进一步推广应用。

Abstract:

OBJECTIVE To establish sensitive indexes for the rational application of perioperative prophylactic use of antibiotics. METHODS The sensitivity index of rational application of perioperative prophylactic use of antibiotics was preliminarily established by searching literatures, the Delphi method was adopted to conduct 2 rounds of letter consultation for 36 pharmaceutical and medical inspectors respectively, and the results were statistically sorted out. RESULTS The sensitive indexes of rational application of perioperative prophylactic use of antibiotics constructed include 3 first-level indexes, 9 second-level indexes and 16 third-level indexes. The effective recovery rates of 2 rounds of expert letter inquiries were 90% and 100%. The authoritative coefficient of the second round was 0.83, and the overall coordination coefficient was 0.370, there were statistically significant(P<0.01). CONCLUSION This study constructs the perioperative sensitive indicators for the rational application of antibacterial drugs for preventive use in the perioperative period, which meets the proactiveness, authority and consistency standards of various experts, and is worthy of further popularization and application.