| 引用本文: | 谢珍,桑晶,高行,张霄鹏,何立成,康桦,李杨,匡荣.化妆品毒理学试验方法的标准比对[J].中国现代应用药学,2021,38(24):3097-3101. |
| XIE Zhen,SANG Jing,GAO Hang,ZHANG Xiaopeng,HE Licheng,KANG Hua,LI Yang,KUANG Rong.Standard Comparison of Toxicological Test Methods for Cosmetics[J].Chin J Mod Appl Pharm(中国现代应用药学),2021,38(24):3097-3101. |
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| 化妆品毒理学试验方法的标准比对 |
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谢珍1, 桑晶1, 高行1, 张霄鹏2, 何立成1, 康桦1, 李杨1, 匡荣1
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1.浙江省食品药品检验研究院, 国家药品监督管理局化妆品动物替代试验技术重点实验室, 杭州 310052;2.杭州瑞旭科技集团有限公司, 杭州 310052
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| 摘要: |
| 化妆品行业的快速发展离不开标准化的技术支撑，标准化对于推动技术进步、规范市场秩序、促进国际贸易起到重要的作用。本文对毒理学试验方法中的急性经皮毒性试验、亚慢性经皮毒性试验、致畸试验的国内外相关标准进行梳理和比对，分析目前标准存在的具体问题并提出建议。 |
| 关键词: 化妆品 急性经皮毒性试验 亚慢性经皮毒性试验 致畸试验 标准比对 |
| DOI：10.13748/j.cnki.issn1007-7693.2021.24.008 |
| 分类号:R991 |
| 基金项目: |
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| Standard Comparison of Toxicological Test Methods for Cosmetics |
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XIE Zhen1, SANG Jing1, GAO Hang1, ZHANG Xiaopeng2, HE Licheng1, KANG Hua1, LI Yang1, KUANG Rong1
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1.Zhejiang Institute for Food and Drug Control, NMPA Key Laboratory for Animal Alternative Testing Technology of Cosmetics, Hangzhou 310052, China;2.Hangzhou REACH Technology Group Co., Ltd., Hangzhou 310052, China
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| Abstract: |
| The rapid development of the cosmetics industry can't be separated from the standardization of technical support, standardization plays an important role in promoting technological progress, regulating market order, and promoting international trade. This paper compare domestic and foreign standards for acute dermal toxicity test, subchronic dermal toxicity test and teratogenicity test, and analysis the specific problems of the current standards and make recommendations. |
| Key words: cosmetics acute dermal toxicity test subchronic dermal toxicity test teratogenicity test standard comparison |
