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引用本文:黄静,丁群力,吴伦.药源性胸腔积液的研究进展[J].中国现代应用药学,2023,40(2):282-288.
HUANG Jing,DING Qunli,WU Lun.Research Progress in Drug-induced Pleural Effusion[J].Chin J Mod Appl Pharm(中国现代应用药学),2023,40(2):282-288.
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药源性胸腔积液的研究进展
黄静1, 丁群力2, 吴伦1
1.宁波大学医学院附属医院, 药学部, 浙江 宁波 315020;2.宁波大学医学院附属医院, 呼吸与危重症科, 浙江 宁波 315020
摘要:
药源性胸腔积液是一种少见的药物引起的肺部不良反应。已发现有较多药物会导致胸腔积液的发生,然而目前对药源性胸腔积液的认知尚少,在临床中常常被忽略。本文根据药物引起胸腔积液的相关病例报道和临床研究等文献资料,阐述药源性胸腔积液的发病率、发病机制、临床表现、诊断流程、治疗手段、相关药物等,以期为临床鉴别药源性胸腔积液提供参考。
关键词:  药源性胸腔积液  嗜酸性胸腔积液  药物狼疮性胸腔积液  肺部不良反应
DOI:10.13748/j.cnki.issn1007-7693.2023.02.021
分类号:
基金项目:宁波市自然科学基金项目(2018A610278);浙江省病理生理学技术研究重点实验室开放基金(201905)
Research Progress in Drug-induced Pleural Effusion
HUANG Jing1, DING Qunli2, WU Lun1
1.The Affiliated Hospital of Medical School of Ningbo University,Department of Pharmacy, Ningbo 315020, China;2.The Affiliated Hospital of Medical School of Ningbo University, Department of Pulmonary and Critical Care Medicine, Ningbo 315020, China
Abstract:
Drug-induced pleural effusion is a rare drug-induced pulmonary adverse reaction. Several drugs have been found to cause pleural effusion, yet drug-induced pleural effusion is still under recognized and often overlooked in clinical practice. This review described the incidence, pathogenesis, clinical manifestations, diagnostic process, treatments and common drugs of drug-induced pleural effusion based on relevant case reports and clinical studies, to provide a clinical reference for the identification of drug-induced pleural effusion.
Key words:  drug-induced pleural effusion  eosinophilic pleural effusion  drug-induced lupus pleurisy  pulmonary adverse reaction
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