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引用本文:李琦,周君美,邢丙聪,杨丙贤,程科军.蜡梅属药用植物分子生物学研究进展[J].中国现代应用药学,2022,39(12):1646-1654.
LI Qi,ZHOU Junmei,XING Bingcong,YANG Bingxian,CHENG Kejun.Research Progress on the Molecular Biology of Genus Chimonanthus Medicinal Plants[J].Chin J Mod Appl Pharm(中国现代应用药学),2022,39(12):1646-1654.
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蜡梅属药用植物分子生物学研究进展
李琦,周君美,邢丙聪,杨丙贤,程科军
1.浙江农林大学, 浙江省特色中药资源保护与创新利用重点实验室, 杭州 311300;2.丽水市农林科学研究院, 浙江 丽水 323000;3.浙江理工大学生命科学与医药学院, 杭州 310018
摘要:
蜡梅属植物有很高的观赏和药用价值,具有抗氧化、抗菌、抗病毒、镇痛等药理活性。然而,现今研究多关注其种质资源、品种分类、化学成分和临床应用等方面,缺乏分子生物学方向的系统总结。本文通过整理近年来基因组学、分子标记、分子鉴定、转录组学和功能基因克隆等方向的研究结果对蜡梅属药用植物的系统进化、遗传多样性、分类鉴定、次生代谢、抗逆机制及生长发育过程等多个方面的研究进展进行系统梳理,并就当前亟需解决的问题和研究前景进行展望,以期为加快蜡梅属药用植物的深度开发应用提供理论参考和研究思路。
关键词:  蜡梅属  分子生物学  研究进展
DOI:10.13748/j.cnki.issn1007-7693.2022.12.021
分类号:R915
基金项目:浙江省特色中药资源保护与创新利用重点实验室开放基金(2021E10013);浙江省基础公益研究计划(LGN20H280001);丽水市重点研发计划项目(2020ZDYF04)
Research Progress on the Molecular Biology of Genus Chimonanthus Medicinal Plants
LI Qi1,2, ZHOU Junmei3, XING Bingcong1,2, YANG Bingxian3,4, CHENG Kejun1,2,3
1.Zhejiang A&2.F University, Zhejiang Provincial Key Laboratory of Resources Protection and Innovation of Traditional Chinese Medicine, Hangzhou 311300, China;3.Lishui Institute of Agriculture and Forestry Sciences, Lishui 323000, China;4.College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China
Abstract:
The plants of genus Chimonanthus have high ornamental and medicinal value. It has antioxidant, antibacterial, antiviral, analgesic and other pharmacological activities. However, current research focus mostly on its germplasm resources, species classification, chemical composition and clinical application, and lacks a systematic summary of molecular biology. This article sorted out the research results of genomics, molecular markers, molecular identification, transcriptomics and functional gene cloning, in order to systematically summarized the progress of phylogenetic evolution, genetic diversity, taxonomic identification, secondary metabolism, stress resistance mechanism, growth and development of medicinal plants of the genus Chimonanthus. And the current urgent problems and research prospects were prospected, in order to provide theoretical reference and research ideas for accelerating the in-depth development and application of medicinal plants of the genus Chimonanthus.
Key words:  genus Chimonanthus  molecular biology  research progress
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