1例布鲁氏菌感染性心内膜炎合并脊柱炎患者的药学监护

Pharmaceutical Care for A Patient with Brucella Infective Endocarditis and Spondylitis

关键词:  布鲁氏菌病  心内膜炎  脊柱炎  药学监护

Key words:  brucellosis  infective endocarditis  spondylitis  pharmaceutical care

摘要:

目的 探讨布鲁氏菌感染性心内膜炎合并脊柱炎患者的治疗方案以及临床药师在治疗中发挥的作用。方法 临床药师参与1例布鲁氏菌感染性心内膜炎合并脊柱炎患者的治疗过程，结合基因检测和INR监测结果，协助医师制定药物治疗方案。针对药物相互作用导致的抗凝影响，及时调整华法林剂量以达到理想目标值，同时提供患者有效的药学监护及用药教育。结果 医师采纳了临床药师的合理化建议，治疗过程中患者未出现不良反应，病情好转后出院。结论 临床药师对患者实施全程化的药学监护，在临床治疗中发挥了积极作用。

Abstract:

OBJECTIVE To explore the therapeutic regimen of brucella infective endocarditis with spondylitis and the role of clinical pharmacists in the treatment. METHODS By participating in the treatment process of a patient with brucella infectious endocarditis and spondylitis, clinical pharmacists assisted clinicians to establish medication regimen combined with genetic testing and INR monitoring results. In view of the anticoagulant effect caused by drug interaction, pharmacists adjusted the warfarin dose timely in order to achieve the ideal target, provided patients effective pharmaceutical care and medical education at the same time. RESULTS The clinicians adopted the treatment suggestions proposed by clinical pharmacists and no adverse reactions occurred during the treatment. After the condition was improved, the patient was discharged. CONCLUSION Clinical pharmacists play a positive role in clinical therapy by implementing whole-process pharmaceutical care for patients.