| 引用本文: | 叶玲,叶娟,党雪菲,翟青,金凤华,杜琼.抗肿瘤药物诱导脱发的相关性研究进展[J].中国现代应用药学,2023,40(7):994-1000. |
| YE Ling,YE Juan,DANG Xuefei,ZHAI Qing,JIN Fenghua,DU Qiong.Research Progress on the Correlation of Antitumor Drug Induced Alopecia[J].Chin J Mod Appl Pharm(中国现代应用药学),2023,40(7):994-1000. |
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| 抗肿瘤药物诱导脱发的相关性研究进展 |
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叶玲1, 叶娟2, 党雪菲3, 翟青1,4,5, 金凤华6, 杜琼1,4,5
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1.复旦大学附属肿瘤医院闵行分院, 药剂科, 上海 200240;2.太湖县中医院检验科, 安徽 安庆 246400;3.复旦大学附属肿瘤医院闵行分院, 肿瘤内科, 上海 200240;4.复旦大学附属肿瘤医院药剂科, 上海 200030;5.复旦大学上海医学院肿瘤学系, 上海 200032;6.合肥市食品药品检验中心, 合肥 238000
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| 摘要: |
| 脱发是肿瘤患者常见的不良反应之一。抗肿瘤药物包括细胞毒性化疗药物、靶向药物、免疫检查点抑制剂和内分泌药物等,均可不同程度地诱导患者脱发。虽然脱发不会危及患者生命,与其他药物不良反应相比,脱发也往往被医师所忽视,但是脱发对患者外在形象、性取向及自尊心等均有影响,有些患者甚至还会出现焦虑或抑郁现象,导致他们的生活质量进一步降低。因此本文对抗肿瘤药物导致脱发的相关文献进行综述,以期为肿瘤患者脱发提供临床参考价值。 |
| 关键词: 抗肿瘤药物 脱发 预防与治疗 |
| DOI：10.13748/j.cnki.issn1007-7693.20222167 |
| 分类号:R979.1 |
| 基金项目:上海市闵行区卫生健康系统优秀青年医技人才和药学人才培养项目(mwyjyx16) |
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| Research Progress on the Correlation of Antitumor Drug Induced Alopecia |
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YE Ling1, YE Juan2, DANG Xuefei3, ZHAI Qing1,4,5, JIN Fenghua6, DU Qiong1,4,5
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1.Minhang Branch, Fudan University Shanghai Cancer Center, Department of Pharmacy, Shanghai 200240, China;2.Clinical Laboratory, Taihu County Hospital of Traditional Chinese Medicine, Anqing 246400, China;3.Minhang Branch, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai 200240, China;4.Department of Pharmacy, Shanghai Cancer Center, Fudan University, Shanghai 200030, China;5.Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China;6.Hefei Center for Food and Drug Control, Hefei 238000, China
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| Abstract: |
| Alopecia is probably one of the common adverse reactions for oncological patients. Antineoplastic drugs, including cytotoxic chemotherapy drugs, targeted agents, immune checkpoint inhibitors and endocrine drugs could induce alopecia to varying degrees. Although hair loss is not life-threatening, and it is often underestimated by physicians compared to other adverse drug reactions. But it negatively influences body image, sexuality and self-esteem. Even some patients experienced anxiety or depression, which further reduced their quality of life. Therefore, this article reviews the literature related to hair loss caused by anti-tumor drugs, in order to provide clinical reference value for cancer patients with hair loss. |
| Key words: anti-cancer agents alopecia prevention and treatment |
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