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引用本文:史丛晶,白浩东,李雨昕,李彪,彭东辉,曾元宁,王秋红.基于熵权法结合灰色关联法和TOPSIS法的不同产地知母及盐知母质量评价研究[J].中国现代应用药学,2023,40(7):873-880.
SHI Congjing,BAI Haodong,LI Yuxin,LI Biao,PENG Donghui,ZENG Yuanning,WANG Qiuhong.Study on Quality Evaluation of Anemarrhenae Rhizoma and Salt Anemarrhenae Rhizoma from Different Producing Areas by Gray Correlation Method and TOPSIS Method Based on Entropy Weight Method[J].Chin J Mod Appl Pharm(中国现代应用药学),2023,40(7):873-880.
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基于熵权法结合灰色关联法和TOPSIS法的不同产地知母及盐知母质量评价研究
史丛晶1, 白浩东2, 李雨昕2, 李彪2, 彭东辉2, 曾元宁1, 王秋红1
1.广东药科大学中药学院, 广州 510006;2.黑龙江中医药大学药学院/教育部北药基础与应用研究重点实验室/黑龙江中药及天然药物药效物质基础研究重点实验室, 哈尔滨 150040
摘要:
目的 利用熵权法结合灰色关联法和TOPSIS法建立知母质量评价模型,评价不同产地知母及其炮制品盐知母的质量。方法 以水分、芒果苷、知母皂苷BⅡ、多糖总糖、糖蛋白及糖醛酸的含量和多糖得率作为检测指标,以熵权法计算权重,结合灰色关联法与TOPSIS法对各项指标进行统计分析,建立知母质量评价模型,综合考察忻州、安国和汉中3个产地共15个批次的知母及其炮制品盐知母的质量。结果 不同产地不同批次的知母各指标水平大不相同;将知母炮制前后各项指标进行对比,发现盐炙后水分降低,皂苷减少,多糖含量增加;15批知母及炮制品盐知母质量排序结果TOPSIS与灰色关联分析基本一致。结论 基于熵权法的灰色关联法-TOPSIS法建立的质量评价模型方便有效,可用于知母质量评价。
关键词:  知母  质量评价  熵权法  灰色关联法  TOPSIS法
DOI:10.13748/j.cnki.issn1007-7693.20222577
分类号:R284.1
基金项目:国家重点研发计划项目(2018YFC1707100)
Study on Quality Evaluation of Anemarrhenae Rhizoma and Salt Anemarrhenae Rhizoma from Different Producing Areas by Gray Correlation Method and TOPSIS Method Based on Entropy Weight Method
SHI Congjing1, BAI Haodong2, LI Yuxin2, LI Biao2, PENG Donghui2, ZENG Yuanning1, WANG Qiuhong1
1.School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China;2.School of Pharmacy, Heilongjiang University of Chinese Medicine, Key Laboratory of Basic and Application Research of Beiyao, Ministry of Education, Heilongjiang Key Laboratory of Traditional Chinese Medicine and Natural Medicine Pharmacodynamic Material Bases, Harbin 150040, China
Abstract:
OBJECTIVE To establish a quality evaluation model of Anemarrhenae Rhizoma using the entropy weight method combined with the gray correlation method and the TOPSIS method for evaluating the quality of Anemarrhenae Rhizoma and its processed products from different origins. METHODS The contents of water, mangiferin, timosaponin B II, total polysaccharide, glycoprotein and uronic acid and polysaccharide yield were chosen as detection indexes for Anemarrhenae Rhizoma, the weight was calculated by entropy weight method, and the indexes were statistically analyzed by gray correlation method and TOPSIS method. Through statistical analysis, a quality evaluation model of Anemarrhenae Rhizoma was established to comprehensively inspect the quality of 15 batches of Anemarrhenae Rhizoma from 3 production areas, including Xinzhou, Anguo and Hanzhong, and its processed products. RESULTS The indexes of Anemarrhenae Rhizoma from different regions and batches were quite different. Comparing the changes before and after processing, it was found that the moisture content decreased, the saponin content decreased, and the polysaccharide content increased. Fifteen batches of Anemarrhenae Rhizoma and processed products quality ranking results TOPSIS were in good consistency with the gray relational analysis. CONCLUSION The quality evaluation model is established by the combined application of gray correlation method and TOPSIS method based on entropy weight method, it is simple and effective, and can be used for the quality evaluation of Anemarrhenae Rhizoma.
Key words:  Anemarrhenae Rhizoma  quality evaluation  entropy method  gray correlation method  TOPSIS method
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