抗肿瘤药物的基础与转化研究助推临床治疗

Basic and Translational Research on Antitumor Drugs Promotes Clinical Therapy

关键词:  抗肿瘤药物  药物靶点  先导化合物  智能递送

Key words:  antitumor drug  drug target  lead compound  intelligent delivery

摘要:

恶性肿瘤已成为严重威胁人类健康的主要公共卫生问题之一。随着医药科技的发展，肿瘤患者的生存率有了明显提升。但是，现有治疗策略远远无法满足临床需求，目前仍存在可用药物少、不良反应严重等问题。为进一步推进肿瘤患者的临床治疗，本期推出了“抗肿瘤药物研究与转化”专栏，分别从“抗肿瘤药物靶点及先导化合物发现”及“抗肿瘤药物的智能递送转化研究”两大主题开展深入探讨，以期为肿瘤患者的临床治疗提供药物新靶点和治疗新策略，助推抗肿瘤创新药物的研发。

Abstract:

Malignant tumors have emerged as a significant public health problem, posing a grave threat to the human health. With the development of medical technology, the survival rate of tumor patients has shown remarkable improvement. However, the existing treatment strategies are far from meeting the clinical needs, and problems are still existed such as few available drugs and serious adverse reactions. To further advance the clinical treatment of tumor patients, this issue presents the column of “Antitumor Drug Research and Translation”, which is divided into two major topics, “the discovery of antitumor drug target and lead compound” and “intelligent delivery of antitumor drugs for translation research”. This column aims to provide novel drug targets and therapeutic strategies for the clinical treatment of tumor patients, thereby boosting the development of innovative anti-tumor drugs.