铁脂代谢与代谢性疾病及天然产物防治的研究进展

Research progress of iron lipid metabolism and metabolic diseases and prevention of natural products

关键词:  铁脂代谢  代谢性疾病  天然产物

Key words:  Iron and lipid metabolism  Metabolic disease  Natural product

摘要:

铁是人体生长发育不可或缺的营养元素,对心血管具有保护作用,其丰度变化和代谢都会影响机体的生理和病理状态。目前研究证实,铁过载会促进胆固醇的合成,加重脂质代谢紊乱。体内脂质代谢紊乱易诱发相关代谢性疾病的发生与发展,并增加相关危险因素爆发的隐患。本文通过对铁脂代谢与代谢性疾病及天然产物通过铁代谢途径防治疾病进行综述,旨在为代谢性疾病及相关疾病的机制深入研究和靶点药物研发提供更有力的参考依据。

Abstract:

Iron is an indispensable nutritional element for human growth and development. It has a protective effect on cardiovascular. The changes and metabolism of iron can affect the physiological and pathological state of the body. Current research has confirmed that iron overload will promote the synthesis of cholesterol and increase lipid metabolism disorders. Lipid metabolic disorders in the body easily induce the occurrence and development of related metabolic diseases, and increase the hidden dangers of the outbreak of relevant risk factors. This article reviews iron and lipid metabolic and other metabolic diseases and natural products to prevent diseases through iron metabolic pathway, which aims to provide more powerful references for in-depth research on the mechanism of metabolic diseases and related diseases and target drug research and development.